Treatments
Rejuran Injection (Rejuran Healer)
Results & Korea Price
Written by BeautyCoordi Editorial TeamMedically reviewed by
Dr. Park HwonhamDR.BAQUO4 min read

Contents · 9
- 01What results can you expect from Rejuran?
- 02How many sessions, and how far apart?
- 03Getting Rejuran in Korea: planning your trip
- 04Does Rejuran hurt?
- 05Downtime, side effects and makeup
- 06Rejuran, Rejuran Eye or Rejuran S?
- 07How much does Rejuran cost in Korea?
- 08Rejuran with Ultherapy, Shurink or lasers
- 09FAQ
Rejuran is a Korean skin booster that injects purified salmon DNA fragments (PN) into the dermis to help skin repair itself. It is not a filler: the goal is smoother texture, softer fine lines and firmer skin, built up over a course of sessions.
Rejuran at a glance
- Best for: rough texture, fine lines, thin or tired-looking skin
- Sessions: usually 3 sessions, at least 3–4 weeks apart, then maintenance every few months
- Downtime: small bumps for about a day; bruises, if any, 1–2 weeks; go easy on makeup for 2–3 days
- Not for: adding volume or lifting sagging contours
What results can you expect from Rejuran?
Patients usually describe their skin as smoother, softer and with more of a glow. Changes build gradually: one session can make skin feel more hydrated, but texture and firmness improve more clearly over the first course.
How it works:
- Injection: tiny amounts are placed in the upper dermis, densely across the face.
- Signal: as PN breaks down, it acts on fibroblasts (through the adenosine A2A receptor), which is thought to support collagen production and calm inflammation.
- Repair: the skin's support structure fills in little by little over several weeks.
Much of this mechanism comes from cell and animal studies, so the honest way to think about Rejuran is "a treatment that helps skin recover", not a dramatic transformation. In a Korean randomized trial around the eyes, PN injections performed about as well as hyaluronic acid injections overall and improved roughness and pores more.
How many sessions, and how far apart?

BeforeAfter sessions
BeforeAfter 3 sessions| Phase | Typical plan |
|---|---|
| First course | 3 sessions, at least 3–4 weeks apart |
| When you notice it | often around the 2nd–3rd session |
| Maintenance | every few months, depending on your skin |
Not sure how many sessions your skin needs? Ask us before you book your trip.
Ask on WhatsAppGetting Rejuran in Korea: planning your trip
Because sessions are spaced at least three to four weeks apart, a short trip usually fits one session. Common ways to plan it:
- One session per visit: come back three to four weeks later, or on your next trip.
- Book it early in your stay: bumps usually settle in about a day, but bruises can last longer, so avoid the day before photos, events or your flight home.
- Combine with lifting: if you are also getting Ultherapy, Shurink or a laser, Rejuran is done last on the same day.
Does Rejuran hurt?
Yes, more than most skin boosters. Thin areas such as the forehead and around the eyes and mouth are the most sensitive.
- Numbing cream: applied for 40–60 minutes before starting
- Injector device: a machine designed to make the injections less painful
- Sedation: an option for patients who are very anxious about pain
Downtime, side effects and makeup
| Reaction | Usually lasts |
|---|---|
| Small raised bumps at injection points | about a day |
| Redness and swelling | hours to a few days |
| Bruising | 1–2 weeks, if it happens |
Rarely, infection, firm nodules or allergic reactions can occur. Every treatment has some risk, so tell the clinic straight away if swelling or pain lasts.
Tell the clinic first if you are allergic to fish or salmon, have inflammation or a skin condition in the area, are pregnant or breastfeeding, or take medicine that makes you bleed easily.
Rejuran, Rejuran Eye or Rejuran S?
| Product | What is different | Used for |
|---|---|---|
| Rejuran Healer | the original | texture, fine lines and firmness across the face |
| Rejuran Eye | lower viscosity, spreads in thin skin | fine lines, friction pigmentation and dark circles under the eyes |
| Rejuran S | made for scars | depressed acne scars |
Rejuran Eye's volume effect is temporary. If the under-eye area looks hollow from lost volume, a volume treatment is usually the better fit.
How much does Rejuran cost in Korea?
Prices vary between clinics because the conditions vary. Compare these on the same basis:
- How many cc are used (full face or a smaller area)
- Whether a sealed, genuine product is opened in front of you
- Whether numbing and soothing care are included
- For event prices, conditions such as first visit only or session limits
If price matters most, other brands with the same PN ingredient can be a more affordable alternative. Current package prices, including clinic visit support in English, are listed on the DR.BAQUO packages page.
Rejuran with Ultherapy, Shurink or lasers
Lifting treatments work on contour, and Rejuran works on the skin itself, so many patients combine them.
FAQ
Is one Rejuran session enough?
One session can make skin feel smoother and more hydrated, but texture and firmness usually change more clearly after the first course of three.
Are Rejuran results permanent?
No. Skin keeps ageing, so most people continue with maintenance sessions every few months after the first course.
Is salmon DNA safe?
Rejuran uses purified PN and is sold as a medical device product. Studies so far mostly report mild reactions, but they are small and short, so mention any fish allergy before treatment.
Sources
- Lampridou S et al. The Effectiveness of Polynucleotides in Esthetic Medicine — A Systematic Review. J Cosmet Dermatol, 2025
- Lee YJ et al. Comparison of the effects of polynucleotide and hyaluronic acid fillers on periocular rejuvenation — a randomized, double-blind, split-face trial. J Dermatolog Treat, 2022
- Park KY et al. Long-chain polynucleotide filler for skin rejuvenation — efficacy and complications in five patients. Dermatol Ther, 2016
- Marques C et al. From PDRNs to PNs — Bridging the Gap Between Scientific Definitions, Molecular Insights, and Clinical Applications. Biomolecules, 2025
Contents · 9
- 01What results can you expect from Rejuran?
- 02How many sessions, and how far apart?
- 03Getting Rejuran in Korea: planning your trip
- 04Does Rejuran hurt?
- 05Downtime, side effects and makeup
- 06Rejuran, Rejuran Eye or Rejuran S?
- 07How much does Rejuran cost in Korea?
- 08Rejuran with Ultherapy, Shurink or lasers
- 09FAQ
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This page is general information, not medical advice. Decide on any treatment after consulting a medical professional.




